Thurlow Dan is the founder of the Helix, a cult that promises to cure loneliness. With its communes and speed-dating, mixers and confession sessions, the Helix has become a national phenomenon - and attracted the attention of governments worldwide. But Thurlow, camped out in his Cincinnati headquarters, is lonely - for his ex-wife, Esme, and their daughter, whom he hasn't seen in ten years. Esme, for her part, is a covert agent who has spent her life spying on Thurlow, mostly to protect him from the law. Now, with her superiors demanding results, she recruits four misfits to botch a reconnaissance mission in Cincinnati. But when Thurlow takes them hostage, he ignites a siege of the Helix House that will change all their lives forever.